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CDK2 inhibitor 73

CAS No. 2079895-42-2

CDK2 inhibitor 73( CDK2-IN-73 | CDK2 IN 73 | CDK2IN73 | CDK2 inhibitor 73 )

Catalog No. M13236 CAS No. 2079895-42-2

A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CDK2 inhibitor 73
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).
  • Description
    A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CDK2-IN-73 | CDK2 IN 73 | CDK2IN73 | CDK2 inhibitor 73
  • Pathway
    Angiogenesis
  • Target
    CDK
  • Recptor
    CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2079895-42-2
  • Formula Weight
    442.497
  • Molecular Formula
    C23H18N6O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20.83 mg/mL (47.07 mM)
  • SMILES
    O=S(C1=CC=C(NC2=NC(C3=CC(C4=CC=CC=C4)=CC=C3)=C5N=CNC5=N2)C=C1)(N)=O
  • Chemical Name
    4-((6-([1,1'-biphenyl]-3-yl)-9H-purin-2-yl)amino) benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Coxon CR, et al. J Med Chem. 2017 Mar 9;60(5):1746-1767.
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