CDK2 inhibitor 73 ( CDK2-IN-73; CDK2 IN 73; CDK2IN73; CDK2 inhibitor 73 )

Catalog No. M13236 CAS No. 2079895-42-2

COA

Datasheet

HNMR

HPLC

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Product Name

CDK2 inhibitor 73
Note

Research use only, not for human use.
Brief Description

A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).
Description

A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).
Synonyms

CDK2-IN-73; CDK2 IN 73; CDK2IN73; CDK2 inhibitor 73
Pathway

Angiogenesis
Target

CDK
Recptor

CDK
Research Area

——
Indication

——

CAS Number

2079895-42-2
Formula Weight

442.50
Molecular Formula

C23H18N6O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=S(C1=CC=C(NC2=NC(C3=CC(C4=CC=CC=C4)=CC=C3)=C5N=CNC5=N2)C=C1)(N)=O
Chemical Name

4-((6-([1,1'-biphenyl]-3-yl)-9H-purin-2-yl)amino) benzenesulfonamide

1. Coxon CR, et al. J Med Chem. 2017 Mar 9;60(5):1746-1767.

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